目的观察多囊卵巢综合征(PCOS)患者口服来曲唑促排卵后行尿黄体生成素(LH)试纸自我监测与阴道超声监测排卵的效果。
方法募集PCOS患者56例,于月经第3~7天每日给予来曲唑1片(2.5mg/d)行促排卵。根据地域分布确定为尿LH试纸自我监测组(试纸组,27例)和阴道超声监测组(B超组,29例)。均于月经第10天开始监测排卵。适时指导同房。后期均给予黄体支持10d。停药7d观察是否月经来潮,医院抽血查HCG,判断是否妊娠。
结果两组的年龄、体重指数(BMI)、不育年限均无统计学差异。B超组29例共行77周期,试纸组27例共行68周期。B超组的排卵率与累积妊娠率分别为77.92%和58.62%,高于试纸组(64.7%、40.74%),但差异无统计学意义。B超组的总周期妊娠率(22.07%)与尿LH试纸组(16.17%)比较,差异亦无统计学意义。
结论PCOS患者中用来曲唑促排卵后行尿LH试纸自我监测与超声监测排卵有同等的效果。
多囊卵巢综合征;黄体生成素试纸;阴道超声;排卵;来曲唑
CompparisionefficacybetweenurinaryL.Handtransvaginalultrasoundformoniteringovulation
WANGGai1,2,ZHAOYong2,LIULingling2,WANGAi-ming2*
1.AnhuiMedicalUniversity,Hefei
2.DepartmentofObstetricsGynecology,NavyGeneralHospital,Beijing
Objective:Comparetotheeffectofself-monitoringbyluteinizinghormrcourse(LH)urineovulationtestormonitoringovulationbytransvaginalultrasoundinpolycysticovarysyndrome(PCOS)patientstreatedwithoralletrozole.
Methods:Thearomataseinhibitorletrozolewasgivenorallyinadoseof2.5mgondays3–7ofmenstrualcycleinthePCOSpatients.ThePCOSpatientsweredividedintotwogroups:theLHtestgroupandthetransvaginalultrasoundgroup.Allmonitoringovulationstartedfromthe10thdayofthemenstrualcycle.Eachwomanwasaskedtohavetimedintercourseinduecourse.Afterovulationwasobserved,thepatientsweregivenlutealphasesupportfor10days.Seeifthemenstruating
cameafterthedrugwasstoppedfor7days,thendeterminingthepregnancywhetherornotbyapregnancytestpaperorcheckingbloodHCGinthehospital.
Results:Therewerenostatisticallysignificantdifferenceinage,durationofinfertility,BMIbetweeninthetwogroup.Theovulationrateandcumulative
pregnancyratewassignificantlyhigherinthegroupoftransvaginalultrasound(77.92%,58.62%)专科治疗白斑医院北京看白癜风哪家医院专业